Let-7a regulates EV secretion and mitochondrial oxidative phosphorylation by targeting SNAP23 in colorectal cancer

BACKGROUND: MicroRNAs (miRNAs) are abundant in tumor-derived extracellular vesicles (EVs) and the functions of extracellular miRNA to recipient cells have been extensively studied with tumorigenesis. However, the role of miRNA in EV secretion from cancer cells remains unknown. METHODS: qPCR and bioi...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Liu, You Dong, Zhuang, Xiao Peng, Cai, Dong Lan, Cao, Can, Gu, Qi Sheng, Liu, Xue Ni, Zheng, Bin Bin, Guan, Bing Jie, Yu, Liang, Li, Ji Kun, Ding, Hui Bin, Yan, Dong Wang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807815/
https://ncbi.nlm.nih.gov/pubmed/33446221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01813-6
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