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A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques

Infants and young children are the groups at greatest risk for severe disease resulting from Plasmodium falciparum infection. We previously demonstrated in mice that a protein vaccine composed of the chemokine macrophage inflammatory protein 3α genetically fused to the minimally truncated circumspor...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Luo, Kun, Gordy, James T., Zavala, Fidel, Markham, Richard B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7807052/
https://ncbi.nlm.nih.gov/pubmed/33441615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79427-3
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