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Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway

Endothelial progenitor cells (EPCs) improve endothelial impairment, which in turn restores endothelial function in patients with heart failure (HF). In the present study, we tested whether fenofibrate, with its anti-inflammatory and vasoprotective effects, could improve myocardial function by activa...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Huang, Wen-Pin, Yin, Wei-Hsian, Chen, Jia-Shiong, Huang, Po-Hsun, Chen, Jaw-Wen, Lin, Shing-Jong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806979/
https://ncbi.nlm.nih.gov/pubmed/33441969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-80984-4
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