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Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway

Endothelial progenitor cells (EPCs) improve endothelial impairment, which in turn restores endothelial function in patients with heart failure (HF). In the present study, we tested whether fenofibrate, with its anti-inflammatory and vasoprotective effects, could improve myocardial function by activa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Wen-Pin, Yin, Wei-Hsian, Chen, Jia-Shiong, Huang, Po-Hsun, Chen, Jaw-Wen, Lin, Shing-Jong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806979/
https://ncbi.nlm.nih.gov/pubmed/33441969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-80984-4
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