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Fenofibrate attenuates doxorubicin-induced cardiac dysfunction in mice via activating the eNOS/EPC pathway

Endothelial progenitor cells (EPCs) improve endothelial impairment, which in turn restores endothelial function in patients with heart failure (HF). In the present study, we tested whether fenofibrate, with its anti-inflammatory and vasoprotective effects, could improve myocardial function by activa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Huang, Wen-Pin, Yin, Wei-Hsian, Chen, Jia-Shiong, Huang, Po-Hsun, Chen, Jaw-Wen, Lin, Shing-Jong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806979/
https://ncbi.nlm.nih.gov/pubmed/33441969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-80984-4
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