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Crystal structure and DNA cleavage mechanism of the restriction DNA glycosylase R.CcoLI from Campylobacter coli

While most restriction enzymes catalyze the hydrolysis of phosphodiester bonds at specific nucleotide sequences in DNA, restriction enzymes of the HALFPIPE superfamily cleave N-glycosidic bonds, similar to DNA glycosylases. Apurinic/apyrimidinic (AP) sites generated by HALFPIPE superfamily proteins...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Miyazono, Ken-ichi, Wang, Delong, Ito, Tomoko, Tanokura, Masaru
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806768/
https://ncbi.nlm.nih.gov/pubmed/33441677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79537-y
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