Angiotensin II type 1a receptor loss ameliorates chronic tubulointerstitial damage after renal ischemia reperfusion

We investigate whether suppressing the activation of the angiotensin II type 1a receptor (AT1a) can ameliorate severe chronic tubulointerstitial damage (TID) after renal ischemia reperfusion (IR) using AT1a knockout homozygous (AT1a(−/−)) male mice. To induce severe chronic TID after renal IR, unila...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Fujita, Yoko, Ichikawa, Daisuke, Sugaya, Takeshi, Ohata, Keiichi, Tanabe, Jun, Inoue, Kazuho, Hoshino, Seiko, Togo, Tatsuru, Watanabe, Minoru, Kimura, Kenjiro, Shibagaki, Yugo, Kamijo-Ikemori, Atsuko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806698/
https://ncbi.nlm.nih.gov/pubmed/33441837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80209-0
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