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The mitochondrial permeability transition phenomenon elucidated by cryo-EM reveals the genuine impact of calcium overload on mitochondrial structure and function

Mitochondria have a remarkable ability to uptake and store massive amounts of calcium. However, the consequences of massive calcium accumulation remain enigmatic. In the present study, we analyzed a series of time-course experiments to identify the sequence of events that occur in a population of gu...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Strubbe-Rivera, Jasiel O., Schrad, Jason R., Pavlov, Evgeny V., Conway, James F., Parent, Kristin N., Bazil, Jason N.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806632/
https://ncbi.nlm.nih.gov/pubmed/33441863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80398-8
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