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Modification and validation of the Endopep-mass spectrometry method for botulinum neurotoxin detection in liver samples with application to samples collected during animal botulism outbreaks

Botulinum neurotoxins (BoNTs) are the most potent toxins known and they cause the paralytic disease botulism in humans and animals. In order to diagnose botulism, active BoNT must be detected in biological material. Endopep-MS is a sensitive and selective method for serum samples, based on antibody...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: Tevell Åberg, Annica, Karlsson, Ida, Hedeland, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7806574/
https://ncbi.nlm.nih.gov/pubmed/33119784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-020-03001-z
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