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Improved Detection of Botulinum Neurotoxin Serotype A by Endopep-MS through Peptide Substrate Modification

Botulinum neurotoxins (BoNTs) are a family of seven toxin serotypes that are the most toxic substances known to man. Intoxication with BoNT causes flaccid paralysis and can lead to death if untreated with serotype specific antibodies. Supportive care, including ventilation, may be necessary. Rapid a...

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Bibliografische gegevens
Gepubliceerd in:Anal Biochem
Hoofdauteurs: Wang, Dongxia, Baudys, Jakub, Ye, Yiming, Rees, Jon C., Barr, John R., Pirkle, James L., Kalb, Suzanne R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618377/
https://ncbi.nlm.nih.gov/pubmed/23017875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2012.09.021
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