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Optimization of peptide substrates for botulinum neurotoxin E improves detection sensitivity in the Endopep-MS assay

Botulinum neurotoxins (BoNTs) produced by Clostridium botulinum are the most poisonous substances known to mankind. It is essential to have a simple, quick and sensitive method for the detection and quantification of botulinum toxin in various media, including complex biological matrices. Our labora...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Wang, Dongxia, Krilich, Joan, Baudys, Jakub, Barr, John R., Kalb, Suzanne R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583364/
https://ncbi.nlm.nih.gov/pubmed/25232998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2014.08.026
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