Longitudinal effect of disease-modifying therapy on tricuspid regurgitant velocity in children with sickle cell anemia

Elevated tricuspid regurgitant velocity (TRV) ≥2.5 m/s is a predictor of disease severity in adults and children with sickle cell anemia (SCA), but how disease-modifying therapies (DMTs) affect this biomarker is incompletely understood. We investigated the effect of DMTs on TRV elevation in children...

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Pubblicato in:Blood Adv
Autori principali: Rai, Parul, Joshi, Vijaya M., Goldberg, Jason F., Yates, Amber M., Okhomina, Victoria I., Penkert, Rhiannon, Ataga, Kenneth I., Kang, Guolian, Hankins, Jane S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
Soggetti:
Clinical Trials and Observations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805333/
https://ncbi.nlm.nih.gov/pubmed/33570630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003197
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