Polarized mitochondria as guardians of NK cell fitness

Distinct metabolic demands accompany lymphocyte differentiation into short-lived effector and long-lived memory cells. How bioenergetics processes are structured in innate natural killer (NK) cells remains unclear. We demonstrate that circulating human CD56(Dim) (NKDim) cells have fused mitochondria...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Surace, Laura, Doisne, Jean-Marc, Escoll, Pedro, Marie, Solenne, Dardalhon, Valerie, Croft, Carys, Thaller, Anna, Topazio, Davide, Sparaneo, Angelo, Cama, Antonia, Musumeci, Olimpia, d’Ecclesia, Aurelio, Buchrieser, Carmen, Taylor, Naomi, Di Santo, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805327/
https://ncbi.nlm.nih.gov/pubmed/33570622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003458
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