Cynaroside inhibits Leishmania donovani UDP-galactopyranose mutase and induces reactive oxygen species to exert antileishmanial response

Cynaroside, a flavonoid, has been shown to have antibacterial, antifungal and anticancer activities. Here, we evaluated its antileishmanial properties and its mechanism of action through different in silico and in vitro assays. Cynaroside exhibited antileishmanial activity in time- and dose-dependen...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Tabrez, Shams, Rahman, Fazlur, Ali, Rahat, Alouffi, Abdulaziz S., Akand, Sajjadul Kadir, Alshehri, Bader Mohammed, Alshammari, Fahdah Ayed, Alam, Aftab, Alaidarous, Mohammed A., Banawas, Saeed, Dukhyil, Abdul Aziz Bin, Rub, Abdur
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2021
Assuntos:
Bioinformatics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805024/
https://ncbi.nlm.nih.gov/pubmed/33367614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20203857
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