Cynaroside inhibits Leishmania donovani UDP-galactopyranose mutase and induces reactive oxygen species to exert antileishmanial response

Cynaroside, a flavonoid, has been shown to have antibacterial, antifungal and anticancer activities. Here, we evaluated its antileishmanial properties and its mechanism of action through different in silico and in vitro assays. Cynaroside exhibited antileishmanial activity in time- and dose-dependen...

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Dades bibliogràfiques
Publicat a:Biosci Rep
Autors principals: Tabrez, Shams, Rahman, Fazlur, Ali, Rahat, Alouffi, Abdulaziz S., Akand, Sajjadul Kadir, Alshehri, Bader Mohammed, Alshammari, Fahdah Ayed, Alam, Aftab, Alaidarous, Mohammed A., Banawas, Saeed, Dukhyil, Abdul Aziz Bin, Rub, Abdur
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2021
Matèries:
Bioinformatics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805024/
https://ncbi.nlm.nih.gov/pubmed/33367614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20203857
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