Cynaroside inhibits Leishmania donovani UDP-galactopyranose mutase and induces reactive oxygen species to exert antileishmanial response

Cynaroside, a flavonoid, has been shown to have antibacterial, antifungal and anticancer activities. Here, we evaluated its antileishmanial properties and its mechanism of action through different in silico and in vitro assays. Cynaroside exhibited antileishmanial activity in time- and dose-dependen...

Full description

Saved in:
Bibliographic Details
Published in:Biosci Rep
Main Authors: Tabrez, Shams, Rahman, Fazlur, Ali, Rahat, Alouffi, Abdulaziz S., Akand, Sajjadul Kadir, Alshehri, Bader Mohammed, Alshammari, Fahdah Ayed, Alam, Aftab, Alaidarous, Mohammed A., Banawas, Saeed, Dukhyil, Abdul Aziz Bin, Rub, Abdur
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2021
Subjects:
Bioinformatics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7805024/
https://ncbi.nlm.nih.gov/pubmed/33367614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20203857
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items