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A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia
Apelin and arginine-vasopressin (AVP) are conversely regulated by osmotic stimuli. We therefore hypothesized that activating the apelin receptor (apelin-R) with LIT01-196, a metabolically stable apelin-17 analog, may be beneficial for treating the Syndrome of Inappropriate Antidiuresis, in which AVP...
Tallennettuna:
| Julkaisussa: | Nat Commun |
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| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7804859/ https://ncbi.nlm.nih.gov/pubmed/33436646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20560-y |
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