Disease-related cortical thinning in presymptomatic granulin mutation carriers

Mutations in the granulin gene (GRN) cause familial frontotemporal dementia. Understanding the structural brain changes in presymptomatic GRN carriers would enforce the use of neuroimaging biomarkers for early diagnosis and monitoring. We studied 100 presymptomatic GRN mutation carriers and 94 nonca...

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Detaylı Bibliyografya
Yayımlandı:Neuroimage Clin
Asıl Yazarlar: Borrego-Écija, Sergi, Sala-Llonch, Roser, van Swieten, John, Borroni, Barbara, Moreno, Fermín, Masellis, Mario, Tartaglia, Carmela, Graff, Caroline, Galimberti, Daniela, Laforce, Robert, Rowe, James B, Finger, Elizabeth, Vandenberghe, Rik, Tagliavini, Fabrizio, de Mendonça, Alexandre, Santana, Isabel, Synofzik, Matthis, Ducharme, Simon, Levin, Johannes, Danek, Adrian, Gerhard, Alex, Otto, Markus, Butler, Chris, Frisoni, Giovanni, Sorbi, Sandro, Heller, Carolin, Bocchetta, Martina, Cash, David M, Convery, Rhian S, Moore, Katrina M, Rohrer, Jonathan D, Sanchez-Valle, Raquel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2020
Konular:
Regular Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804836/
https://ncbi.nlm.nih.gov/pubmed/33418170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2020.102540
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