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Prediction of kinase inhibitors binding modes with machine learning and reduced descriptor sets

Protein kinases are receiving wide research interest, from drug perspective, due to their important roles in human body. Available kinase-inhibitor data, including crystallized structures, revealed many details about the mechanism of inhibition and binding modes. The understanding and analysis of th...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Abdelbaky, Ibrahim, Tayara, Hilal, Chong, Kil To
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804204/
https://ncbi.nlm.nih.gov/pubmed/33436888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80758-4
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