HLA genotype-clinical phenotype correlations in multiple sclerosis and neuromyelitis optica spectrum disorders based on Japan MS/NMOSD Biobank data

HLA genotype-clinical phenotype correlations are not established for multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). We studied HLA-DRB1/DPB1 genotype–phenotype correlations in 528 MS and 165 NMOSD cases using Japan MS/NMOSD Biobank materials. HLA-DRB1*04:05, DRB1*15:01...

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Publicado no:Sci Rep
Main Authors: Watanabe, Mitsuru, Nakamura, Yuri, Sato, Shinya, Niino, Masaaki, Fukaura, Hikoaki, Tanaka, Masami, Ochi, Hirofumi, Kanda, Takashi, Takeshita, Yukio, Yokota, Takanori, Nishida, Yoichiro, Matsui, Makoto, Nagayama, Shigemi, Kusunoki, Susumu, Miyamoto, Katsuichi, Mizuno, Masanori, Kawachi, Izumi, Saji, Etsuji, Ohashi, Takashi, Shimohama, Shun, Hisahara, Shin, Nishiyama, Kazutoshi, Iizuka, Takahiro, Nakatsuji, Yuji, Okuno, Tatsusada, Ochi, Kazuhide, Suzumura, Akio, Yamamoto, Ken, Kawano, Yuji, Tsuji, Shoji, Hirata, Makoto, Sakate, Ryuichi, Kimura, Tomonori, Shimizu, Yuko, Nagaishi, Akiko, Okada, Kazumasa, Hayashi, Fumie, Sakoda, Ayako, Masaki, Katsuhisa, Shinoda, Koji, Isobe, Noriko, Matsushita, Takuya, Kira, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804194/
https://ncbi.nlm.nih.gov/pubmed/33436735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79833-7
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