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Identification of significantly mutated subnetworks in the breast cancer genome

Recent studies showed that somatic cancer mutations target genes that are in specific signaling and cellular pathways. However, in each patient only a few of the pathway genes are mutated. Current approaches consider only existing pathways and ignore the topology of the pathways. For this reason, ne...

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Publicat a:Sci Rep
Autors principals: Ajwad, Rasif, Domaratzki, Michael, Liu, Qian, Feizi, Nikta, Hu, Pingzhao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804148/
https://ncbi.nlm.nih.gov/pubmed/33436820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80204-5
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