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Identification of significantly mutated subnetworks in the breast cancer genome

Recent studies showed that somatic cancer mutations target genes that are in specific signaling and cellular pathways. However, in each patient only a few of the pathway genes are mutated. Current approaches consider only existing pathways and ignore the topology of the pathways. For this reason, ne...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ajwad, Rasif, Domaratzki, Michael, Liu, Qian, Feizi, Nikta, Hu, Pingzhao
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804148/
https://ncbi.nlm.nih.gov/pubmed/33436820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80204-5
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