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Identification of significantly mutated subnetworks in the breast cancer genome

Recent studies showed that somatic cancer mutations target genes that are in specific signaling and cellular pathways. However, in each patient only a few of the pathway genes are mutated. Current approaches consider only existing pathways and ignore the topology of the pathways. For this reason, ne...

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書目詳細資料
發表在:Sci Rep
Main Authors: Ajwad, Rasif, Domaratzki, Michael, Liu, Qian, Feizi, Nikta, Hu, Pingzhao
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2021
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804148/
https://ncbi.nlm.nih.gov/pubmed/33436820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80204-5
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