Insights into genome recoding from the mechanism of a classic +1-frameshifting tRNA

While genome recoding using quadruplet codons to incorporate non-proteinogenic amino acids is attractive for biotechnology and bioengineering purposes, the mechanism through which such codons are translated is poorly understood. Here we investigate translation of quadruplet codons by a +1-frameshift...

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Publicat a:Nat Commun
Autors principals: Gamper, Howard, Li, Haixing, Masuda, Isao, Miklos Robkis, D., Christian, Thomas, Conn, Adam B., Blaha, Gregor, Petersson, E. James, Gonzalez, Ruben L., Hou, Ya-Ming
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803779/
https://ncbi.nlm.nih.gov/pubmed/33436566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20373-z
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