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Structural basis of GABARAP-mediated GABA(A) receptor trafficking and functions on GABAergic synaptic transmission
GABA(A) receptors (GABA(A)Rs) are the primary fast inhibitory ion channels in the central nervous system. Dysfunction of trafficking and localization of GABA(A)Rs to cell membranes is clinically associated with severe psychiatric disorders in humans. The GABARAP protein is known to support the stabi...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7803741/ https://ncbi.nlm.nih.gov/pubmed/33436612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20624-z |
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