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Structural basis of GABARAP-mediated GABA(A) receptor trafficking and functions on GABAergic synaptic transmission

GABA(A) receptors (GABA(A)Rs) are the primary fast inhibitory ion channels in the central nervous system. Dysfunction of trafficking and localization of GABA(A)Rs to cell membranes is clinically associated with severe psychiatric disorders in humans. The GABARAP protein is known to support the stabi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nat Commun
मुख्य लेखकों: Ye, Jin, Zou, Guichang, Zhu, Ruichi, Kong, Chao, Miao, Chenjian, Zhang, Mingjie, Li, Jianchao, Xiong, Wei, Wang, Chao
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803741/
https://ncbi.nlm.nih.gov/pubmed/33436612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20624-z
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