Structural basis of GABARAP-mediated GABA(A) receptor trafficking and functions on GABAergic synaptic transmission

GABA(A) receptors (GABA(A)Rs) are the primary fast inhibitory ion channels in the central nervous system. Dysfunction of trafficking and localization of GABA(A)Rs to cell membranes is clinically associated with severe psychiatric disorders in humans. The GABARAP protein is known to support the stabi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ye, Jin, Zou, Guichang, Zhu, Ruichi, Kong, Chao, Miao, Chenjian, Zhang, Mingjie, Li, Jianchao, Xiong, Wei, Wang, Chao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803741/
https://ncbi.nlm.nih.gov/pubmed/33436612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20624-z
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