Inhibition of PAR-1 delays aging via activating AMPK in C. elegans

The antagonistic pleiotropy theory of aging suggests that genes essential for growth and development are likely to modulate aging later in life. Previous studies in C. elegans demonstrate that inhibition of certain developmentally essential genes during adulthood leads to significant lifespan extens...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Wu, Di, Cai, Waijiao, Zhang, Xuan, Lan, Jianfeng, Zou, Lina, Chen, Samuel J., Wu, Zixing, Chen, Di
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803586/
https://ncbi.nlm.nih.gov/pubmed/33232266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104180
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