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Downregulated genes by silencing MYC pathway identified with RNA-SEQ analysis as potential prognostic biomarkers in gastric adenocarcinoma

MYC overexpression is a common phenomenon in gastric carcinogenesis. In this study, we identified genes differentially expressed with a downregulated profile in gastric cancer (GC) cell lines with silenced MYC. The TTLL12, CDKN3, CDC16, PTPRA, MZT2B, UBE2T genes were validated using qRT-PCR, western...

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Bibliografski detalji
Izdano u:Aging (Albany NY)
Glavni autori: Heitor da Silva Maués, Jersey, Ferreira Ribeiro, Helem, de Maria Maués Sacramento, Raquel, Maia de Sousa, Rafael, Pereira de Tommaso, Raíssa, Dourado Kovacs Machado Costa, Bruno, Cardoso Soares, Paulo, Pimentel Assumpção, Paulo, de Fátima Aquino Moreira-Nunes, Caroline, Mário Rodriguez Burbano, Rommel
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803532/
https://ncbi.nlm.nih.gov/pubmed/33351778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202260
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