Downregulated genes by silencing MYC pathway identified with RNA-SEQ analysis as potential prognostic biomarkers in gastric adenocarcinoma

MYC overexpression is a common phenomenon in gastric carcinogenesis. In this study, we identified genes differentially expressed with a downregulated profile in gastric cancer (GC) cell lines with silenced MYC. The TTLL12, CDKN3, CDC16, PTPRA, MZT2B, UBE2T genes were validated using qRT-PCR, western...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Heitor da Silva Maués, Jersey, Ferreira Ribeiro, Helem, de Maria Maués Sacramento, Raquel, Maia de Sousa, Rafael, Pereira de Tommaso, Raíssa, Dourado Kovacs Machado Costa, Bruno, Cardoso Soares, Paulo, Pimentel Assumpção, Paulo, de Fátima Aquino Moreira-Nunes, Caroline, Mário Rodriguez Burbano, Rommel
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803532/
https://ncbi.nlm.nih.gov/pubmed/33351778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202260
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