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Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation

Patients with acute myeloid leukemia (AML) have a median age of 65-70 years at diagnosis. Elderly patients have more chemoresistant disease, and this is partly due to decreased frequencies of favorable and increased frequencies of adverse genetic abnormalities. However, aging-dependent differences m...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Hernandez-Valladares, Maria, Aasebø, Elise, Berven, Frode, Selheim, Frode, Bruserud, Øystein
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803495/
https://ncbi.nlm.nih.gov/pubmed/33349623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.202361
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