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The association of Plk1 with the astrin–kinastrin complex promotes formation and maintenance of a metaphase plate
Errors in mitotic chromosome segregation can lead to DNA damage and aneuploidy, both hallmarks of cancer. To achieve synchronous error-free segregation, mitotic chromosomes must align at the metaphase plate with stable amphitelic attachments to microtubules emanating from opposing spindle poles. The...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7803464/ https://ncbi.nlm.nih.gov/pubmed/33288550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.251025 |
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