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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity

Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease separase. Separase also promotes centriole diseng...

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Bibliografske podrobnosti
Main Authors: Thein, Kerstin H., Kleylein-Sohn, Julia, Nigg, Erich A., Gruneberg, Ulrike
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064855/
https://ncbi.nlm.nih.gov/pubmed/17664331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701163
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