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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity

Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease separase. Separase also promotes centriole diseng...

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Hlavní autoři: Thein, Kerstin H., Kleylein-Sohn, Julia, Nigg, Erich A., Gruneberg, Ulrike
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064855/
https://ncbi.nlm.nih.gov/pubmed/17664331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701163
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