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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity
Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease separase. Separase also promotes centriole diseng...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064855/ https://ncbi.nlm.nih.gov/pubmed/17664331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701163 |
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