Computational Drug Repositioning Identifies Potentially Active Therapies for Chordoma

BACKGROUND: Chordomas are aggressive bone tumors that often recur despite maximal resection and adjuvant radiation. To date there are no Food and Drug Administration (FDA)-approved chemotherapies. Computational drug repositioning is an expanding approach to identify pharmacotherapies for clinical tr...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neurosurgery
Main Authors: Traylor, Jeffrey I, Sheppard, Hadley E, Ravikumar, Visweswaran, Breshears, Jonathan, Raza, Shaan M, Lin, Charles Y, Patel, Shreyaskumar R, DeMonte, Franco
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Research—Laboratory
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803434/
https://ncbi.nlm.nih.gov/pubmed/33017025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuros/nyaa398
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