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Probing the Mechanism of Photoaffinity Labeling by Dialkyldiazirines through Bioorthogonal Capture of Diazoalkanes

Dialkyldiazirines have emerged as reagents of choice for biological photoaffinity labeling studies. The mechanism of crosslinking has dramatic consequences for biological applications where instantaneous labeling is desirable, as carbene insertions display different chemoselectivity and are much fas...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: O’Brien, Jessica G. K., Jemas, Andrew, Asare-Okai, Papa Nii, Ende, Christopher W. am, Fox, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7802889/
https://ncbi.nlm.nih.gov/pubmed/33259213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c02714
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