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Multiple Alu Exonization in 3′UTR of a Primate-Specific Isoform of CYP20A1 Creates a Potential miRNA Sponge
Alu repeats contribute to phylogenetic novelties in conserved regulatory networks in primates. Our study highlights how exonized Alus could nucleate large-scale mRNA–miRNA interactions. Using a functional genomics approach, we characterize a transcript isoform of an orphan gene, CYP20A1 (CYP20A1_Alu...
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| Gepubliceerd in: | Genome Biol Evol |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7802813/ https://ncbi.nlm.nih.gov/pubmed/33434274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evaa233 |
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