Maternal folic acid impacts DNA methylation profile in male rat offspring implicated in neurodevelopment and learning/memory abilities

BACKGROUND: Periconceptional folic acid (FA) supplementation not only reduces the incidence of neural tube defects, but also improves cognitive performances in offspring. However, the genes or pathways that are epigenetically regulated by FA in neurodevelopment were rarely reported. METHODS: To eluc...

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Vydáno v:Genes Nutr
Hlavní autoři: Wang, Xinyan, Li, Zhenshu, Zhu, Yun, Yan, Jing, Liu, Huan, Huang, Guowei, Li, Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7802276/
https://ncbi.nlm.nih.gov/pubmed/33430764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12263-020-00681-1
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