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Periconceptional Folic Acid Supplementation Benefit to Development of Early Sensory-Motor Function through Increase DNA Methylation in Rat Offspring

Periconceptional maternal folate levels may alter DNA methylation patterns and health outcomes in offspring. We hypothesized that maternal folic acid supplementation alters fetal neural development through DNA methylation in the fetal brain. Twenty-eight rats were randomly assigned to four groups: t...

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Библиографические подробности
Опубликовано в: :Nutrients
Главные авторы: Li, Wen, Li, Zhenshu, Li, Shou, Wang, Xinyan, Wilson, John X., Huang, Guowei
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872710/
https://ncbi.nlm.nih.gov/pubmed/29494536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10030292
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