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Periconceptional Folic Acid Supplementation Benefit to Development of Early Sensory-Motor Function through Increase DNA Methylation in Rat Offspring

Periconceptional maternal folate levels may alter DNA methylation patterns and health outcomes in offspring. We hypothesized that maternal folic acid supplementation alters fetal neural development through DNA methylation in the fetal brain. Twenty-eight rats were randomly assigned to four groups: t...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Li, Wen, Li, Zhenshu, Li, Shou, Wang, Xinyan, Wilson, John X., Huang, Guowei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872710/
https://ncbi.nlm.nih.gov/pubmed/29494536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10030292
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