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Interleukin-6 promotes primitive endoderm development in bovine blastocysts

BACKGROUND: Interleukin-6 (IL6) was recently identified as an embryotrophic factor in bovine embryos, where it acts primarily to mediate inner cell mass (ICM) size. This work explored whether IL6 affects epiblast (EPI) and primitive endoderm (PE) development, the two embryonic lineages generated fro...

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Détails bibliographiques
Publié dans:BMC Dev Biol
Auteurs principaux: Wooldridge, Lydia K., Ealy, Alan D.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7802221/
https://ncbi.nlm.nih.gov/pubmed/33430761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-020-00235-z
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