Lipoxygenase catalyzed metabolites derived from docosahexaenoic acid are promising antitumor agents against breast cancer

Docosahexaenoic acid (DHA) is known to inhibit breast cancer in the rat. Here we investigated whether DHA itself or select metabolites can account for its antitumor action. We focused on metabolites derived from the lipoxygenase (LOX) pathway since we previously showed that they were superior anti-p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Kun-Ming, Thompson, Henry, Vanden-Heuvel, John P., Sun, Yuan-Wan, Trushin, Neil, Aliaga, Cesar, Gowda, Krishne, Amin, Shantu, Stanley, Bruce, Manni, Andrea, El-Bayoumy, Karam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801725/
https://ncbi.nlm.nih.gov/pubmed/33431978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79716-x
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