Lipoxygenase catalyzed metabolites derived from docosahexaenoic acid are promising antitumor agents against breast cancer

Docosahexaenoic acid (DHA) is known to inhibit breast cancer in the rat. Here we investigated whether DHA itself or select metabolites can account for its antitumor action. We focused on metabolites derived from the lipoxygenase (LOX) pathway since we previously showed that they were superior anti-p...

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Wydane w:Sci Rep
Główni autorzy: Chen, Kun-Ming, Thompson, Henry, Vanden-Heuvel, John P., Sun, Yuan-Wan, Trushin, Neil, Aliaga, Cesar, Gowda, Krishne, Amin, Shantu, Stanley, Bruce, Manni, Andrea, El-Bayoumy, Karam
Format: Artigo
Język:Inglês
Wydane: Nature Publishing Group UK 2021
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801725/
https://ncbi.nlm.nih.gov/pubmed/33431978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79716-x
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