Antagomir-mediated suppression of microRNA-134 reduces kainic acid-induced seizures in immature mice

MicroRNAs are short non-coding RNAs that negatively regulate protein levels and perform important roles in establishing and maintaining neuronal network function. Previous studies in adult rodents have detected upregulation of microRNA-134 after prolonged seizures (status epilepticus) and demonstrat...

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Publicat a:Sci Rep
Autors principals: Campbell, Aoife, Morris, Gareth, Heller, Janosch P., Langa, Elena, Brindley, Elizabeth, Worm, Jesper, Jensen, Mads Aaboe, Miller, Meghan T., Henshall, David C., Reschke, Cristina R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801672/
https://ncbi.nlm.nih.gov/pubmed/33431894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79350-7
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