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Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA‐134

OBJECTIVE: Inhibition of microRNA‐134 by an oligonucleotide antagomir (ant‐134) has been shown to produce powerful antiseizure effects in multiple models of epilepsy. However, to successfully translate the treatment to the clinic, it is important to assess what potential adverse effects it may have...

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Publicat a:Epilepsia
Autors principals: Morris, Gareth, Brennan, Gary P., Reschke, Cristina R., Henshall, David C., Schorge, Stephanie
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099438/
https://ncbi.nlm.nih.gov/pubmed/29978460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14475
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