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Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA‐134

OBJECTIVE: Inhibition of microRNA‐134 by an oligonucleotide antagomir (ant‐134) has been shown to produce powerful antiseizure effects in multiple models of epilepsy. However, to successfully translate the treatment to the clinic, it is important to assess what potential adverse effects it may have...

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Detalhes bibliográficos
Publicado no:Epilepsia
Main Authors: Morris, Gareth, Brennan, Gary P., Reschke, Cristina R., Henshall, David C., Schorge, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099438/
https://ncbi.nlm.nih.gov/pubmed/29978460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.14475
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