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Exemplar scoring identifies genetically separable phenotypes of lithium responsive bipolar disorder

Predicting lithium response (LiR) in bipolar disorder (BD) may inform treatment planning, but phenotypic heterogeneity complicates discovery of genomic markers. We hypothesized that patients with “exemplary phenotypes”—those whose clinical features are reliably associated with LiR and non-response (...

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Библиографические подробности
Опубликовано в: :Transl Psychiatry
Главные авторы: Nunes, Abraham, Stone, William, Ardau, Raffaella, Berghöfer, Anne, Bocchetta, Alberto, Chillotti, Caterina, Deiana, Valeria, Degenhardt, Franziska, Forstner, Andreas J., Garnham, Julie S., Grof, Eva, Hajek, Tomas, Manchia, Mirko, Mattheisen, Manuel, McMahon, Francis, Müller-Oerlinghausen, Bruno, Nöthen, Markus M., Pinna, Marco, Pisanu, Claudia, O’Donovan, Claire, Rietschel, Marcella D. C., Rouleau, Guy, Schulze, Thomas, Severino, Giovanni, Slaney, Claire M., Squassina, Alessio, Suwalska, Aleksandra, Turecki, Gustavo, Uher, Rudolf, Zvolsky, Petr, Cervantes, Pablo, del Zompo, Maria, Grof, Paul, Rybakowski, Janusz, Tondo, Leonardo, Trappenberg, Thomas, Alda, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801503/
https://ncbi.nlm.nih.gov/pubmed/33431852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01148-y
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