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FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro

INTRODUCTION: Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase protein frequently overexpressed in cancer and has been linked to an increase in the stem cell population of tumors, resistance to therapy, and metastatic spread. Pharmacological FAK inhibition in pancreatic cancer has receiv...

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Bibliografische gegevens
Gepubliceerd in:Strahlenther Onkol
Hoofdauteurs: Mohamed, A. Allam, Thomsen, Andreas, Follo, Marie, Zamboglou, Costantinos, Bronsert, Peter, Mostafa, Hanan, Amen, Aber, Mekawy, Mohamed, Grosu, Anca L., Brunner, Thomas B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801360/
https://ncbi.nlm.nih.gov/pubmed/32705304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00066-020-01666-0
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