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FAK inhibition radiosensitizes pancreatic ductal adenocarcinoma cells in vitro

INTRODUCTION: Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase protein frequently overexpressed in cancer and has been linked to an increase in the stem cell population of tumors, resistance to therapy, and metastatic spread. Pharmacological FAK inhibition in pancreatic cancer has receiv...

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Detalhes bibliográficos
Publicado no:Strahlenther Onkol
Main Authors: Mohamed, A. Allam, Thomsen, Andreas, Follo, Marie, Zamboglou, Costantinos, Bronsert, Peter, Mostafa, Hanan, Amen, Aber, Mekawy, Mohamed, Grosu, Anca L., Brunner, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801360/
https://ncbi.nlm.nih.gov/pubmed/32705304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00066-020-01666-0
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