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Bersaldegenin-1,3,5-orthoacetate induces caspase-independent cell death, DNA damage and cell cycle arrest in human cervical cancer HeLa cells

CONTEXT: Bufadienolide compounds occur in many plants and animal species and have strong cardiac and anti-inflammatory properties. The compounds have been recently investigated for cytotoxic and antitumor activity. OBJECTIVE: The cytotoxic effect of bersaldegenin-1,3,5-orthoacetate – a bufadienolide...

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Publicat a:Pharm Biol
Autors principals: Stefanowicz-Hajduk, Justyna, Gucwa, Magdalena, Moniuszko-Szajwaj, Barbara, Stochmal, Anna, Kawiak, Anna, Ochocka, J. Renata
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801116/
https://ncbi.nlm.nih.gov/pubmed/33403918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13880209.2020.1866025
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