Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice

INTRODUCTION: Interleukin-34 (IL-34) shares a receptor (cFMS) with colony stimulating factor-1 (CSF-1), and these two ligands mediate macrophage proliferation. However, in contrast to CSF-1, the influence of IL-34 on tubular epithelial cells (TECs) injury remains unclear. We investigated the physiol...

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Udgivet i:PLoS One
Main Authors: Wada, Yukihiro, Iyoda, Masayuki, Matsumoto, Kei, Suzuki, Taihei, Tachibana, Shohei, Kanazawa, Nobuhiro, Honda, Hirokazu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7799787/
https://ncbi.nlm.nih.gov/pubmed/33428678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245340
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