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The PDZ Domain Protein SYNJ2BP Regulates GRK-Dependent Sst2A Phosphorylation and Downstream MAPK Signaling
The somatostatin receptor 2A (SST(2)) is a G-protein-coupled receptor (GPCR) that is expressed in neuroendocrine tissues within the gastrointestinal tract and brain, and is commonly overexpressed in many neuroendocrine tumors. Moreover, SST(2) agonists are used clinically as the primary pharmacologi...
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| Publicado no: | Endocrinology |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7799432/ https://ncbi.nlm.nih.gov/pubmed/33313679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa229 |
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