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Commensal microbiota modulation of natural resistance to virus infection
IFN-Is are crucial mediators of antiviral immunity and homeostatic immune system regulation. However, the source of IFN-I signaling under homeostatic conditions is unclear. We discovered that commensal microbes regulate the IFN-I response through induction of IFNβ by colonic DCs. Moreover, the mecha...
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| Опубликовано в: : | Cell |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7799371/ https://ncbi.nlm.nih.gov/pubmed/33212011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.10.047 |
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