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Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner

Antibiotics are widely used to treat infections in humans. However, the impact of antibiotic use on host cells is understudied. Here we identify an antiviral effect of commonly used aminoglycoside antibiotics. We show that topical mucosal application of aminoglycosides prophylactically increased hos...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Gopinath, Smita, Kim, Myoungjoo V., Rakib, Tasfia, Wong, Patrick W., van Zandt, Michael, Barry, Natasha A., Kaisho, Tsuneyasu, Goodman, Andrew L., Iwasaki, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918160/
https://ncbi.nlm.nih.gov/pubmed/29632368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-018-0138-2
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