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Nuclear Factor Erythroid 2 Related Factor 2 Activator JC-5411 Inhibits Atherosclerosis Through Suppression of Inflammation and Regulation of Lipid Metabolism

Phenethyl isothiocyanate is widely present in cruciferous vegetables with multiple biological effects. Here we reported the antiatherogenic effects and the underlying mechanisms of JC-5411 (Phenethyl isothiocyanate formulation) in vitro and in vivo. Luciferase reporter assay showed that JC-5411 incr...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Jiang, Xinhai, Li, Yining, Wang, Weizhi, Han, Xiaowan, Han, Jiangxue, Chen, Mingzhu, Zhang, Jing, Wang, Chenyin, Li, Shunwang, Luo, Jinque, Wang, Xiao, Xu, Yang, Xu, Yanni, Cheng, Jingcai, Si, Shuyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797784/
https://ncbi.nlm.nih.gov/pubmed/33442380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.532568
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